MRI and Computational Simulation Cardiology Study

Part of paid clinical trials in Palo Alto, California.

Sponsor
Stanford University
Study ID
NCT03149341
Status
Enrolling By Invitation

Conditions

  • Congenital Heart Disease
  • Pulmonary Hypertension

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • Magnetic Resonance Imaging — OTHER
    All subjects will undergo or have already undergone Magnetic Resonance Imaging. Normal volunteers will be used for comparison with subjects. To minimize risk, normal volunteers will NOT undergo anesthesia, sedation or receive intravenous contrast during procedure.

Study Details

The purpose of this study is to (1) quantify cardiovascular anatomy and physiology using magnetic resonance imaging under both resting and exercise conditions in patients who have congenital heart disease and in age-matched normal volunteers, (2) use computer models to reproduce and simulate blood flow in these patients, and then (3) to combine the imaging data and computer models to estimate values which cannot be directly measured and to predict physiological changes induced by exercise and medical or surgical therapies.

Key Dates

Start date
Feb 29, 2008
Status verified
Dec 2024
Primary completion
Jan 31, 2029
Completion
Feb 28, 2029

Study Design

Enrollment
75 participants (estimated)

Arms

  • Arm: Study
    Congenital heart disease or acquired cardiopulmonary disease who will get (or have gotten) and MRI
  • Arm: Normal Volunteers
    No congenital heart disease or acquired cardiopulmonary disease who will get (or have gotten) and MRI

Primary Outcome Measure

Wall Shear Stress [ Time Frame: 20 years ]

Locations (1)

FacilityCityStateZIPSite coordinators
Lucile Packard Children's Hospital at StanfordPalo AltoCalifornia94304-

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Lucile Packard Children's Hospital at Stanford· Palo Alto, CA

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