Follicular Fluid microRNAs in Ovarian Aging and Reproduction

Part of paid clinical trials in Orlando, Florida.

Sponsor
University of Central Florida
Study ID
NCT07214246
Status
Recruiting
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Conditions

  • In Vitro Fertilisation (IVF) Treatment
  • In Vitro Fertilization Outcome
  • InVitro Fertilization
  • Ovarian Aging

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • No Interventions — OTHER
    No interventions for participants

Study Details

The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.

Key Dates

Start date
Sep 22, 2025
Status verified
Oct 2025
Primary completion
Sep 30, 2026
Completion
Sep 30, 2026

Study Design

Enrollment
100 participants (estimated)

Primary Outcome Measure

Identify exosomal miRNAs using RNA sequencing [ Time Frame: 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Central FloridaOrlandoFlorida32827
Amoy Fraser, PhD, CCRP, PMP
[email protected]
4072668742
Britney-Ann Wray, BS, CCRP, CTBS
[email protected]
4072668742
Michal Masternak, PhD (PRINCIPAL_INVESTIGATOR)

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