Identification of Brain Injury Using Portable MRI

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT07197918
Status
Recruiting
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Conditions

  • Cardiac Arrest (CA)
  • Hypoxic-Ischemic Brain Injury

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • portable MRI scanner — DEVICE
    Participants will receive 2-3 portable MRI scans: \<6 hours, 6-24 hours, and within 12 (+/- 12) hours of conventional MRI

Study Details

The goal of this study is to look for brain injury in patients who had a cardiac arrest, using portable brain imaging. The portable nature of this test will also allow for serial imaging so the investigators can understand how brain injury changes over days. The results of this study may allow for bedside imaging to be available at centers without specialized imaging centers and may identify markers of brain injury that help to select the patients most likely to benefit for clinical trials.

Key Dates

Start date
Dec 2, 2025
Status verified
Jan 2026
Primary completion
Apr 30, 2027
Completion
Apr 30, 2027

Study Design

Enrollment
60 participants (estimated)

Arms

  • Arm: Cardiac arrest with Return of Spontaneous Circulation (ROSC)
    All enrolled patients will have two to three portable MRIs ( \<6 hours, 6-24 hours and one within 12 (+/- 12) hours of conventional MRI) and one conventional MRI. Standard of care will occur per the clinical team and this study will not interfere with standard of care.

Primary Outcome Measure

Cortex- DGN HIBI score [ Time Frame: up to 6 hours post cardiac arrest, up to 24 hours post cardiac arrest and within 12 (+/- 12) hours of conventional MRI ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Yale New Haven HospitalNew HavenConnecticut05620-

Find similar trials in New Haven, CT

By research site
Yale New Haven Hospital· New Haven, CT

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