Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Stanford University
Study ID
NCT07130500
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Financial incentives for adherence to long-acting injectable medication — BEHAVIORAL
    This intervention is a randomized controlled trial where patients in the treatment group are offered financial incentives for taking long-acting injectable (LAI) versions of the antipsychotic and substance use disorder medications they need and the control group receives the status quo standard of care.
  • Standard of care with monthly surveys — BEHAVIORAL
    Receives standard outpatient care and incentives for completing monthly surveys.

Study Details

This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance use disorder who are recently discharged from involuntary hospitalization or are at high risk of future involuntary hospitalization. Participants will be randomized to receive financial incentives for adherence to long-acting injectable medications or to a control group.

Key Dates

Start date
Mar 9, 2026
Status verified
Mar 2026
Primary completion
Mar 31, 2029
Completion
Mar 31, 2030

Study Design

Enrollment
1,000 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Financial Incentives for Medication Adherence
    Receives financial incentives for each LAI administered and increasing bonus for consecutive adherence.
  • Active Comparator: Standard of Care
    Receives standard outpatient care and survey incentives only.

Primary Outcome Measure

Adherence to antipsychotic medication [ Time Frame: From start of study to end of study 12 months later; for follow-up, for 12 months after end of study. ]

Locations (5)

FacilityCityStateZIPSite coordinators
Pittsburgh MercyPittsburghPennsylvania15203-
UPMC Bellefield TowersPittsburghPennsylvania15213-
UPMC Franklin BuildingPittsburghPennsylvania15203-
UPMC Oxford BuildingPittsburghPennsylvania15213-
UPMC Western Psychiatric HospitalPittsburghPennsylvania15213-

Find similar trials in Pittsburgh, PA

By condition
Schizophrenia
By specialty
PsychiatryMental healthBehavioral health
By research site
Pittsburgh Mercy· Pittsburgh, PAUPMC Bellefield Towers· Pittsburgh, PAUPMC Franklin Building· Pittsburgh, PAUPMC Oxford Building· Pittsburgh, PAUPMC Western Psychiatric Hospital· Pittsburgh, PA

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