Parathyroidectomy and Mobility Study

Part of paid clinical trials in Gainesville, Florida.

Sponsor
University of Florida
Study ID
NCT07103876
Status
Recruiting
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Conditions

  • Hyperparathyroidism
  • Mobility
  • Parathyroid

Eligibility Criteria

Sex
ALL
Age
60 Years - 100 Years
Healthy Volunteers
Not accepted

Study Details

This study evaluates whether surgical removal of the parathyroid gland (parathyroidectomy) improves physical function and mobility in older adults with primary hyperparathyroidism (PHPT). PHPT, a common endocrine disorder in older adults, is associated with reduced muscle strength, mobility, and quality of life. This prospective observational study will enroll up to 80 participants aged 60 and older undergoing parathyroidectomy at UF Health. Participants will complete physical performance tests, wear an Actigraph device to assess physical activity, and provide blood samples for biomarker analysis at pre- and post-operative time points. The goal is to characterize changes in physical function and activity following surgery and to identify biomarkers that may predict mobility improvements. Findings will help inform future larger-scale studies and could expand surgical indications for PHPT in older adults.

Key Dates

Start date
Aug 15, 2025
Status verified
Jul 2025
Primary completion
Nov 30, 2026
Completion
Mar 31, 2027

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: Adults aged 60 and above with primary hyperparathyroidism
    Participants who are undergoing a parathyroidectomy at UF health

Primary Outcome Measure

Distance Walked in Six-Minute Walk Test (6MWT) [ Time Frame: At pre-operative assessment and at 3 month post-operative assessment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Clinical and Translational Research BuildingGainesvilleFlorida32610
Recruitment Coordinators
[email protected]
352-273-5919

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By research site
Clinical and Translational Research Building· Gainesville, FL

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