Impact of Supplemental Fiber on Gut and Vascular Health Related in Obesity Phenotypes

Part of paid clinical trials in Muncie, Indiana.

Sponsor
Ball State University
Study ID
NCT07095426
Status
Recruiting
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Conditions

  • Healthy Participants
  • Metabolic Syndrome
  • Metabolically Abnormal Obesity
  • Metabolically Healthy Obesity

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • inulin — DIETARY_SUPPLEMENT
    6g inulin from chicory root per day for one week and 12g inulin per day for eight weeks dissolved into cool or room temperature liquid

Study Details

Based on prior research, the investigators are interested in whether an intervention targeting gut health (supplemental fiber for 9 weeks total) will improve vascular health in individuals with obesity. Additionally, the investigators are interested in if this response differs based on whether individuals with obesity have very few heart disease risk factors or several heart disease risk factors.

Key Dates

Start date
May 20, 2025
Status verified
Jul 2025
Primary completion
Nov 30, 2026
Completion
May 31, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Inulin Supplement
    Participants will consume 6g of pre-portioned powdered inulin from chicory root daily for one week followed by 12g daily for eight weeks. Participants will fully dissolve it into a habitual cool or room temperature beverage to drink around the same time each day.

Primary Outcome Measure

Serum Soluble Cluster of Differentiation 14 (sCD14) [ Time Frame: Through study completion, up to 1.5 years. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Health Professions BuildingMuncieIndiana47306
Bryant Keirns, PhD
[email protected]
765-285-8356

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By research site
Health Professions Building· Muncie, IN

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