NYU Epilepsy Self-Management Study

Part of paid clinical trials in Brooklyn, New York.

Sponsor
NYU Langone Health
Study ID
NCT07087821
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • UPLIFT — BEHAVIORAL
    UPLIFT is an 8-week epilepsy self-management programs delivered to small groups of people with epilepsy (PWE) by Webex. UPLIFT is focused on self-management of depressive symptoms. Each weekly session is 1 hour long and is comprised of a check-in period, teaching on the week's topic, group discussion, a skill-building exercise and a home practice assignment.
  • PACES — BEHAVIORAL
    PACES is an 8-week epilepsy self-management programs delivered to small groups of people with epilepsy (PWE) by Webex. PACES focuses on general epilepsy self-management. Each weekly session is 1 hour long and is comprised of a check-in period, teaching on the week's topic, group discussion, a skill-building exercise and a home practice assignment.
  • Enhanced Usual Care — BEHAVIORAL
    Participants receive referrals to local epilepsy support groups.

Study Details

The investigators will conduct two-arm randomized controlled trials (RCTs) comparing effects of UPLIFT vs. enhanced usual care and PACES vs. enhanced usual care, respectively, on quality of life, depressive symptoms and seizures over 12 months in NYU patients with epilepsy.

Key Dates

Start date
Sep 16, 2025
Status verified
May 2026
Primary completion
Sep 29, 2027
Completion
Sep 29, 2027

Study Design

Enrollment
108 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH

Arms

  • Experimental: RCT 1: UPLIFT
    Participants in RCT 1 assigned to the UPLIFT arm.
  • Active Comparator: RCT 1: Enhanced Usual Care
    Participants in RCT 1 assigned to the enhanced usual care arm.
  • Experimental: RCT 2: PACES
    Participants in RCT 2 assigned to the PACES arm.
  • Active Comparator: RCT 2: Enhanced Usual Care
    Participants in RCT 2 assigned to the enhanced usual care arm.

Primary Outcome Measure

Number of Participants with Patient Health Questionnaire-9 (PHQ-9) Score <5 [ Time Frame: Baseline ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
NYU Langone Health - NYU Langone Hospital-BrooklynBrooklynNew York11220-
NYU Langone Health - NYU Comprehensive Epilepsy CenterNew YorkNew York10016-

Find similar trials in Brooklyn, NY

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
NYU Langone Health - NYU Langone Hospital-Brooklyn· Brooklyn, NYNYU Langone Health - NYU Comprehensive Epilepsy Center· New York, NY

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