Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07065669
Status
Recruiting
Apply to this trial

Conditions

  • Obsessive-Compulsive Disorder

Eligibility Criteria

Sex
ALL
Age
13 Years - 17 Years
Healthy Volunteers
Not accepted

Interventions

  • Dorsal medial Prefrontal Cortex intermittent theta burst stimulation — DEVICE
    iTBS stimulation of the dmPFC is a FDA-approved treatment for adults with OCD
  • cTBS to ROFC — DEVICE
    continuous theta burst stimulation (cTBS) 1,800 pulses per session

Study Details

This is a pilot study to examine the tolerability, safety and early efficacy of two forms of transcranial magnetic stimulation (TMS) for treating adolescents with Obsessive Compulsive Disorder (OCD) who have experienced limited improvements with usual treatments for OCD in adolescents. The project's primary goal is to examine whether adolescents can complete 3 consecutive weeks of TMS administered 5 days per week, and to describe the type of and how common individual side effects with TMS occur in adolescents with OCD. Participants will: * visit the clinic every weekday for 3 weeks (15 days) to receive TMS treatments * have a brain MRI scan before TMS treatments begins and after finishing all TMS * complete questionnaires and report changes in behavior and physical symptoms

Key Dates

Start date
Jun 1, 2025
Status verified
Jul 2025
Primary completion
Jul 1, 2027
Completion
Jul 1, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Right Orbitofrontal TBS
    continuous theta burst stimulation
  • Active Comparator: TBS of dorsal, medial prefrontal cortex
    intermittent theta burst stimulation (iTBS) will be delivered to the dmPFC

Primary Outcome Measure

Completion rate [ Time Frame: Baseline to completion of all protocol visits, up to 8 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94107
Starlette Khim, BA
[email protected]
415-514-5743
James T McCracken, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in San Francisco, CA

By research site
University of California, San Francisco· San Francisco, CA

Related Studies