Examining the Circadian Timing Effects of the Hypotensive Response to Exercise

Part of paid clinical trials in Newark, Delaware.

Sponsor: Freda Patterson
Study ID: NCT07049783
Status: Recruiting

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Conditions

Circadian Rhythm
Hypertension
Post-Exercise Hypotension
Young Adults

Eligibility Criteria

Sex: ALL
Age: 18 Years - 39 Years
Healthy Volunteers: Not accepted

Interventions

Exercise — BEHAVIORAL
A single standardized, in-lab, 30-minute monitored treadmill exercise session

Study Details

The goal of this study is to learn how exercise timing affects blood pressure in adults with elevated or high blood pressure. Exercise can influence the body's natural 24-hour rhythms, including blood pressure patterns. A single exercise session can lower blood pressure for up to 24 hours, but it is not fully understood how the time-of-day for exercise affects this response. The main question this study aims to answer is: • When the same participant exercises at different times of day (morning, afternoon, or evening), how does this affect the participant's blood pressure over the next 24 hours? Participants will: * Undergo an in-lab assessment of individual biological rhythm that will indicate the clock-time for an individual's biological night * Complete 3 supervised treadmill exercise sessions * 1 in the biological morning (biological night + 10 hours) * 1 in the biological afternoon (biological night + 15 hours) * 1 in the biological evening (biological night + 20 hours) * Complete a 24-hour blood pressure assessment before and after each exercise session