A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Sun Pharma Advanced Research Company Limited
Study ID
NCT07042100
Phase
PHASE1
Status
Recruiting
Apply to this trial

Conditions

  • Advanced Solid Tumors

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Dose level (DL)1 — BIOLOGICAL
    Administered IV every 3 weeks
  • DL2 — BIOLOGICAL
    Administered IV every 3 weeks
  • DL3 — BIOLOGICAL
    Administered IV every 3 weeks
  • DL4 — BIOLOGICAL
    Administered IV every 3 weeks
  • DL5 — BIOLOGICAL
    Administered IV every 3 weeks

Study Details

This is a Phase 1 study of SBO-154 in patients with advanced cancers who are unable to tolerate or have not previously responded to standard therapy available in the country. The study involves multiple doses and takes place at several centers.

Key Dates

Start date
Aug 12, 2025
Status verified
Jun 2026
Primary completion
Aug 31, 2028
Completion
Aug 31, 2030

Study Design

Enrollment
177 participants (estimated)
Allocation
NA
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: SBO-154

Primary Outcome Measure

Incidence of dose-limiting toxicities [ Time Frame: Twenty-one days from the initiation of the first dose of SBO-154 (3 weeks) ]

Central Contacts

Locations (5)

FacilityCityStateZIPSite coordinators
Honorhealth Research InstituteScottsdaleArizona85258
Justin Moser, MD, MBA
[email protected]
480-323-1350
Sarcoma Oncology Research CenterSanta MonicaCalifornia90403
Neil S Chawla, MD
[email protected]
310-552-9999
Yale University - Yale Cancer CenterNew HavenConnecticut06510
So Y Kim, MD
[email protected]
203-407-8002
Hope and Healing Clinical Research LLCHinsdaleIllinois60521
Srilata Gundala, MBBS
[email protected]
630-560-0121
MD Anderson Cancer CenterHoustonTexas77030
Ecaterina Dumbrava, MD
[email protected]
713-792-3934

Find similar trials in Scottsdale, AZ

By research site
Honorhealth Research Institute· Scottsdale, AZSarcoma Oncology Research Center· Santa Monica, CAYale University - Yale Cancer Center· New Haven, CTHope and Healing Clinical Research LLC· Hinsdale, ILMD Anderson Cancer Center· Houston, TX

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