Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Part of paid clinical trials in Newark, New Jersey.

Sponsor
Rutgers, The State University of New Jersey
Study ID
NCT06995638
Status
Recruiting
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Conditions

  • Alzheimer's Disease (AD)
  • Healthy Aging

Eligibility Criteria

Sex
ALL
Age
60 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Web-based Cognitive Training (with strategy) — BEHAVIORAL
    Participants will learn to play a complex online game using specific guidance or strategy.
  • Web-based Cognitive Training (without strategy) — BEHAVIORAL
    Participants will learn to play a complex online game without specific guidance or strategy.

Study Details

Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk. Executive Control is a relevant cognitive target since it declines with aging and is critical for multi-tasking in daily life. The proposed research investigates whether playing a web-based cognitive complex game (the Breakfast Game) impacts cognitive performance in cognitively healthy older adults. To be enrolled in the study, participants will be asked to undergo a cognitive sassessment, health questionnires, and a blood exam. The intervention consist in one educational session on healthy aging, and 10 one-hour cognitive training sessions 2-3 times a week over one month. Participants will be asked to repeat the cognitive assessment within 1-2 weeks after the intervention, and after three months.

Key Dates

Start date
Dec 10, 2025
Status verified
Dec 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
130 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Strategy Training
    Participants will undergo a web-based training protocol that involves playing an online game simulating a breakfast environment, where they will perform everyday activities such as "cooking" and "setting tables" in a multitasking fashion. Participants will learn to play the game using specific strategies to optimize their performance.
  • Active Comparator: Regular Training
    Participants will undergo a web-based training protocol that involves playing an online game simulating a breakfast environment, where they will perform everyday activities such as "cooking" and "setting tables" in a multitasking fashion. Participants will learn to play the game under regular game instructions.
  • No Intervention: Passive Control

Primary Outcome Measure

Changes in the Breakfast Game scores [ Time Frame: Training session 1, week 1; training 10, approximately 4 weeks. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Rutgers New Jersey Medical School, Behavior Health Sciences Building, F-LevelNewarkNew Jersey07103
Thamiris Gonçalves Clinical Research Coordinator, MS
[email protected]
973-972-2977
Ana Staniscia, MA
[email protected]
Sharon Sanz Simon Assistant Professor, Ph.D. (PRINCIPAL_INVESTIGATOR)

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By research site
Rutgers New Jersey Medical School, Behavior Health Sciences Building, F-Level· Newark, NJ

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