Efficacy of Routine Saline Flushing in the Prevention of Nephrostomy Tube Obstructions: A Pilot Study

Conditions

• Nephrostomy

Eligibility Criteria

Sex

ALL

Age

18 Years - 80 Years

Healthy Volunteers

Not accepted

Interventions

• No flushing of the nephrostomy — OTHER
  Subjects allocated to the study intervention group will not flush their nephrostomy tube during the duration of the research study
• Flushing of nephrostomy — OTHER
  Subjects assigned to this cohort will flush their nephrostomy catheter once daily with 10 mL of normal saline

Study Details

The investigators performing this research to study if routine flushing is necessary to prevent obstructions of a nephrostomy tube. This study will evaluate patients that have nephrostomy tube or will have nephrostomy tubes placed as part of their standard clinical care. If participants agree to participate in this study, participants will undergo randomized assignment to either continue to routinely flush the nephrostomy tube with normal saline or not to routinely flush the nephrostomy tube with normal saline. Participantswill be in the study for approximately 3 months if they decide to stay for the whole study.

Key Dates

Start date

Jan 1, 2026

Status verified

Feb 2026

Primary completion

Dec 30, 2026

Completion

Mar 30, 2027

Study Design

Enrollment

20 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Active Comparator: Routine Flushing of Nephrostomy
  Subjects in the routine flushing group will continue to flush their nephrostomy tubes once per day with 10mL of normal saline
• Experimental: No Flushing of Nephrostomy
  Subjects allocated to the study intervention group will not flush their nephrostomy tube during the duration of the research study

Primary Outcome Measure

Tube Obstruction [ Time Frame: 12 weeks ]

Central Contacts

• Yan Epelboym, MD, MPH
  617-732-4763
  [email protected]
• Austin Lai, MD
  617-732-4763
  [email protected]

Locations (1)

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