Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy

Part of paid clinical trials in Durham, North Carolina.

Sponsor
Duke University
Study ID
NCT06986304
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The project will include 30 patients with bladder cancer who are candidates for bladder removal. After signing the consent form, the study team will collect some clinical data, such as age, past medical history, past surgical history, and information about your current disease. At the day of surgery, after putting participants into sleep and before surgery begins, the study team will do a novel ultrasound called "Super-Resolution Ultrasound Localization Microscopy" to check if there is still disease in the bladder. The team will then compare the results of this investigational ultrasound with the final pathology and other imaging studies.

Key Dates

Start date
Oct 28, 2025
Status verified
Apr 2026
Primary completion
Jan 31, 2027
Completion
Apr 30, 2027

Study Design

Enrollment
30 participants (estimated)

Primary Outcome Measure

Presence and stage of residual bladder cancer at the time of RC. [ Time Frame: From enrollment to first post-cystectomy follow-up visit (1 month) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Duke UniversityDurhamNorth Carolina27710
Alireza Ghoreifinejadian, M.D.
919-684-8111
Michael Abern, M.D. (PRINCIPAL_INVESTIGATOR)

Find similar trials in Durham, NC

By condition
Bladder cancer
By specialty
OncologyUrology
By research site
Duke University· Durham, NC

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