Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT06976476
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • IgPro20 — DRUG
    Will be administered in addition to Standard of Care treatment. IgPro20 is intended for subcutaneous administration using an infusion pump

Study Details

The main purpose of this study is to see if IgPro20 can prevent infection in people with multiple myeloma (MM) who have hypogammaglobulinemia from receiving bispecific monoclonal antibodies (BsAbs).

Key Dates

Start date
May 8, 2025
Status verified
Mar 2026
Primary completion
May 8, 2029
Completion
May 8, 2029

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • No Intervention: Standard of Care
    Participants will only be observed
  • Experimental: Standard of Care + IGRT prophylaxis with IgPro20
    Participants will receive IGRT prophylaxis with IgPro20 in addition to standard of care

Primary Outcome Measure

Difference in overall infection rates between Standard of Care participants and participants receiving IgPro20 [ Time Frame: 6 months ]

Central Contacts

Locations (8)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)Basking RidgeNew Jersey10065
Zainab Shahid, MBBS
212-639-6483
Memorial Sloan Kettering Monmouth (All Protocol Activities)MiddletownNew Jersey07748
Zainab Shahnid, MBBS
212-639-6483
Memorial Sloan Kettering Bergen (All Protocol Activities)MontvaleNew Jersey07645
Zainab Shahid, MBBS
212-639-6483
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activity)CommackNew York11725
Zainab Shahid, MBBS
212-639-6483
Memorial Sloan Kettering Westchester (All Protocol Activities)HarrisonNew York10604
Zainab Shahid, MBBS
212-639-6483
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Zainab Shahid, MBBS
212-639-6483
Mount Sinai HospitalNew YorkNew York10029
Cesar Rodriguez, MD
212-241-7873
Memorial Sloan Kettering Nassau (All Protocol Activities)UniondaleNew York11553
Zainab Shahid, MBBS
212-639-6483

Find similar trials in Basking Ridge, NJ

By condition
Multiple myeloma
By specialty
OncologyBlood cancer
By research site
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (All Protocol Activities)· Middletown, NJMemorial Sloan Kettering Bergen (All Protocol Activities)· Montvale, NJMemorial Sloan Kettering Suffolk-Commack (All Protocol Activity)· Commack, NYMemorial Sloan Kettering Westchester (All Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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