Effects of Social Feedback on Intracranial EEG
Part of paid clinical trials in Lebanon, New Hampshire.
- Sponsor
- Trustees of Dartmouth College
- Study ID
- NCT06975800
- Status
- Recruiting
Conditions
- Epilepsy
- Social Influence
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 65 Years
- Healthy Volunteers
- Not accepted
Interventions
- Low social feedback — BEHAVIORALSocial information is provided to participants signaling that the upcoming trial will be low in negative affect and cognitive effort.
- High social feedback — BEHAVIORALSocial information is provided to participants signaling that the upcoming trial will be high in negative affect and cognitive effort.
Study Details
This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked to rate their provider's warmth, competence, and other, similar traits associated with care-competency. They will then complete the picture-induced fear and math portions of the multimodal negative affect task (MNAT) during which iEEG is recorded.
Key Dates
- Start date
- Apr 6, 2023
- Status verified
- May 2025
- Primary completion
- Feb 28, 2027
- Completion
- Feb 28, 2028
Study Design
- Enrollment
- 24 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- CROSSOVER
- Primary purpose
- BASIC_SCIENCE
Arms
- Experimental: Random Order 1: Effects of social feedback on intracranial EEGParticipants experience trials involving presentation of negative affective stimuli and an effort-demanding cognitive task. Trials are preceded by high or low social cues in random order.
- Experimental: Random Order 2: Effects of social feedback on intracranial EEGParticipants experience trials involving presentation of negative affective stimuli and an effort-demanding cognitive task. Trials are preceded by high or low social cues in random order.
Primary Outcome Measure
Negative affect ratings [ Time Frame: Ratings are made 3 to 10 seconds after experiencing each stimulus presented during task performance. ]
Central Contacts
- Tor D Wager, PhD603-646-2196
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03766 | Krzysztof A Bujarski, Doctor of Medicine |
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