Effects of Social Feedback on Intracranial EEG

Part of paid clinical trials in Lebanon, New Hampshire.

Sponsor
Trustees of Dartmouth College
Study ID
NCT06975800
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Low social feedback — BEHAVIORAL
    Social information is provided to participants signaling that the upcoming trial will be low in negative affect and cognitive effort.
  • High social feedback — BEHAVIORAL
    Social information is provided to participants signaling that the upcoming trial will be high in negative affect and cognitive effort.

Study Details

This study aims to assess the impact of social influence on direct neural recordings in human patients undergoing surgical treatment of epilepsy. 24 patients recruited from the Epilepsy Center at Dartmouth Health Medical Center (DHMC) will undergo electrode implantation throughout the brain to localize epileptogenic zones. Patients will be asked to rate their provider's warmth, competence, and other, similar traits associated with care-competency. They will then complete the picture-induced fear and math portions of the multimodal negative affect task (MNAT) during which iEEG is recorded.

Key Dates

Start date
Apr 6, 2023
Status verified
May 2025
Primary completion
Feb 28, 2027
Completion
Feb 28, 2028

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Random Order 1: Effects of social feedback on intracranial EEG
    Participants experience trials involving presentation of negative affective stimuli and an effort-demanding cognitive task. Trials are preceded by high or low social cues in random order.
  • Experimental: Random Order 2: Effects of social feedback on intracranial EEG
    Participants experience trials involving presentation of negative affective stimuli and an effort-demanding cognitive task. Trials are preceded by high or low social cues in random order.

Primary Outcome Measure

Negative affect ratings [ Time Frame: Ratings are made 3 to 10 seconds after experiencing each stimulus presented during task performance. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Dartmouth Hitchcock Medical CenterLebanonNew Hampshire03766
Krzysztof A Bujarski, Doctor of Medicine

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