Metabolic Health, Bones and Nuts During Weight Loss in Adults

Part of paid clinical trials in New Brunswick, New Jersey.

Sponsor
Rutgers, The State University of New Jersey
Study ID
NCT06949280
Status
Recruiting
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Conditions

  • Bone Density
  • Obesity and Overweight
  • Weight Loss

Eligibility Criteria

Sex
ALL
Age
50 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Peanut Snack Experimental — DIETARY_SUPPLEMENT
    Subjects will receive a daily peanut snack and nutrition education-behavior modification instructions for weight loss
  • Nut-free Snack — DIETARY_SUPPLEMENT
    Subjects will receive a daily peanut snack and nutrition education-behavior modification instructions for weight loss

Study Details

The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice but are not consumed frequently enough in older adults. Studies have shown that regular nut consumption is associated with lower adiposity and reduced weight gain, and several dietary pattern studies indicate that nuts and legumes are associated with better bone health. In addition, our preliminary translational data indicates that a higher monounsaturated fatty acid (MUFA) intake is associated with improved bone mineral density (BMD) and quality. Given these findings, the proposed study aims to examine the impact of consuming peanut products on bone health, metabolic health (e.g., serum glucose, insulin, lipids and inflammation), markers of brain and sleep health, and physical function in overweight and obese older adults before and after a six-month weight loss intervention using a randomized controlled design. The results of this study have the potential to provide valuable insights into the role of peanuts as a sources of fatty acids in promoting health and preventing disease in at-risk adults.

Key Dates

Start date
Oct 30, 2025
Status verified
May 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
44 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Peanut
    Peanut products
  • Active Comparator: Nut-free snack
    Grain snack (nut-free)

Primary Outcome Measure

Bone Mineral Density (BMD - hip) [ Time Frame: Change from baseline to 24 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Rutgers University - NJ Inst Food Nutrition & HealthNew BrunswickNew Jersey08901
Principal Investigator
[email protected]
848-932-9403
Research Manager, MS
[email protected]
732-455-2062

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By research site
Rutgers University - NJ Inst Food Nutrition & Health· New Brunswick, NJ

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