Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy

Part of paid clinical trials in Providence, Rhode Island.

Sponsor
Brown University
Study ID
NCT06948058
Status
Recruiting
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Conditions

  • Obesity and Obesity-related Medical Conditions
  • Smoking Cessation

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Electronic Cigarettes (EC) — OTHER
    Participants will receive information about the comparative risk of alternative nicotine products relative to smoking and will be asked to switch to EC for 8 weeks, with EC provided.
  • Nicotine replacement therapy (NRT) — OTHER
    Participants will receive information about the comparative risk of alternative nicotine products relative to smoking and will be asked to switch to combination NRT (transdermal + oral) for 8 weeks, with NRT provided.

Study Details

This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.

Key Dates

Start date
Apr 1, 2025
Status verified
Apr 2026
Primary completion
May 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Electronic Cigarette (EC) Condition
    Participants in this condition will receive the EC intervention.
  • Experimental: Nicotine Replacement Therapy Condition
    Participants in this condition will receive the NRT intervention.
  • No Intervention: No-Product Control Condition (CON)
    Participants in this condition will not receive any alternate nicotine product.

Primary Outcome Measure

number of cigarettes per day [ Time Frame: 2 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Brown UniversityProvidenceRhode Island02912
CRESCENT Research Staff
[email protected]
401-203-5339

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