Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

Part of paid clinical trials in New York, New York.

Sponsor
Weill Medical College of Cornell University
Study ID
NCT01776398
Status
Recruiting
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Conditions

  • Chronic Obstructive Pulmonary Disease (COPD)
  • Idiopathic Pulmonary Fibrosis (IPF)
  • Rheumatoid Arthritis-Associated Interstitial Lung Disease
  • Scleroderma-Associated Interstitial Lung Disease (SSC-ILD)
  • Smoking
  • Smoking Cessation

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

The purpose of this study is to obtain biologic materials from the blood, airways and/or urine of normal individuals and individuals with lung disease. The normal are used to establish a set of normal ranges for various parameters. These provide control information when compared to individuals with various pulmonary diseases, and will help in understanding of the etiology and pathogenesis of various lung diseases. The underlying hypothesis is that the pathologic morphological changes in the airway epithelium must be preceded by changes in the gene expression pattern of the airway epithelium and potentially in macrophages.

Key Dates

Start date
Aug 29, 2012
Status verified
Nov 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2028

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: 1.1 HEALTHY SUBJECTS
    Healthy as defined by those not having lung disease and inclusive of: all races, ethnicities, sex, HIV status, smoking status and multiple birth status, etc., within the general population.
  • Arm: 1.2 SUBJECTS WITH LUNG DISEASE
    Defined by those having lung disease or symptoms of lung disease and inclusive of: all races, ethnicities, sex, HIV status, smoking status and multiple birth status, etc., within the general population)
  • Arm: 2. WCMC/NYPH CLINICAL PATIENTS
    Subjects may be recruited if subjects fit inclusion/exclusion criteria and are deemed eligible to participate as long as informed consent is given. Sample collection will occur during a separate study visit. WCMC/NYPH clinical patients will not undergo any additional procedures listed in this protocol as part of this research study.
  • Arm: 3. PCNY CLINICAL PATIENTS
    Subjects may be recruited if subjects fit inclusion/exclusion criteria and are deemed eligible to participate as long as informed consent is given. Sample collection will occur during a separate study visit. Clinical patients seen at the Pulmonary Consultants of New York will only undergo the nasal sample collection and may be asked to have a blood draw of about 2 teaspoons (9ml).

Primary Outcome Measure

Establishing normal ranges for various parameters [ Time Frame: Participants upon completing the study will be followed up by a phone call seven days after their visit. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Weill Cornell Medical College and Weill Cornell Medical Center, Department of Genetic MedicineNew YorkNew York10065-4870
Niamh Savage
[email protected]
212-746-0284

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By research site
Weill Cornell Medical College and Weill Cornell Medical Center, Department of Genetic Medicine· New York, NY

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