Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults

Part of paid clinical trials in Corvallis, Oregon.

Sponsor
Oregon State University
Study ID
NCT06942351
Status
Recruiting
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Conditions

  • Aging
  • Inflammation Biomarkers

Eligibility Criteria

Sex
ALL
Age
55 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Walnuts — OTHER
    Daily consumption of 1.5 ounces of plain walnuts for 12 weeks
  • Crackers — OTHER
    Daily consumption of non-whole grain crackers for 12 weeks (caloric equivalent to 1.5 ounces of plain walnuts)

Study Details

The purpose of this study is to examine the impact of daily consumption of walnuts for 12 weeks on cognitive function, markers of inflammation and oxidative stress, and the gut microbiome in healthy adults age 55 years and older.

Key Dates

Start date
Jun 9, 2025
Status verified
Apr 2025
Primary completion
Dec 31, 2028
Completion
May 31, 2029

Study Design

Enrollment
80 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Walnuts
    Daily consumption of 1.5 ounces (42.5 g) of plain walnuts for 12 weeks
  • Placebo Comparator: Crackers
    Daily consumption of non-whole grain crackers for 12 weeks (caloric equivalent to 1.5 ounces of plain walnuts)

Primary Outcome Measure

Cognitive function - memory [ Time Frame: 0 and 12 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Oregon State UniversityCorvallisOregon97331
Sandra Uesugi, RN, BSN, MS
[email protected]
541-737-3594
Emily Ho, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
Oregon State University· Corvallis, OR

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