Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System

Part of paid clinical trials in Fairfax, Virginia.

Sponsor
Inova Health Care Services
Study ID
NCT06931561
Status
Recruiting
Apply to this trial

Conditions

  • Cancer

Eligibility Criteria

Sex
ALL
Age
35 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • Whole Body MRI — PROCEDURE
    Whole body MRI
  • Whole Body Ultrasound — PROCEDURE
    Whole Body Ultrasound
  • MCD Assay — DEVICE
    Cancer detection blood test
  • Occupational Exposure Questionnaire — OTHER
    Questionnaire

Study Details

The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters. This study involves an investigational test (cancer blood test) that has not been approved by the U.S. Food and Drug Administration (FDA). Whole-body MRI and whole-body ultrasound are approved by the U.S. Food and Drug Administration (FDA) to be used in the diagnosis of some cancers and is approved for adults and children who present other signs of potential disease. In this study, however, the whole-body MRI and the whole-body ultrasound are considered investigational devices because they are not yet approved for use in healthy adults with no other cancer indications.

Key Dates

Start date
Feb 11, 2025
Status verified
Apr 2025
Primary completion
Sep 30, 2028
Completion
Sep 30, 2028

Study Design

Enrollment
800 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING

Arms

  • Active Comparator: Whole Body MRI
    Prenuvo whole body magnetic resonance imaging
  • Active Comparator: Whole Body Ultrasound
    High frequency sound waves

Primary Outcome Measure

Number of confirmed pre-malignancies detected with each investigational screening tool [ Time Frame: up to 1 year (± 2 months) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Inova Schar Cancer - Saville Cancer Screening and Prevention CenterFairfaxVirginia22031
Salman Baig
[email protected]
571-472-3500
Bryan Bassig, PhD
[email protected]
(571) 472-3500
Rebecca Kaltman, MD (PRINCIPAL_INVESTIGATOR)
Bryan Bassig, PhD (SUB_INVESTIGATOR)
Jennifer Lund, DO (SUB_INVESTIGATOR)

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By research site
Inova Schar Cancer - Saville Cancer Screening and Prevention Center· Fairfax, VA

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