Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function

Part of paid clinical trials in Boulder, Colorado.

Sponsor
University of Colorado, Boulder
Study ID
NCT06906536
Status
Enrolling By Invitation

Conditions

  • Able Bodied
  • INCOMPLETE SPINAL CORD INJURY (ASIA D)

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Acute Intermittent Hypoxia (AIH) — OTHER
    4 consecutive days of 15, 1.5 min episodes at 9% O2 (AIH) alternating with 21% O2 at 1 min intervals

Study Details

The goal of this study is to clarify mechanisms of acute intermittent hypoxia and to examine the effect on lower limb function in persons with chronic, incomplete spinal cord injury.

Key Dates

Start date
Mar 1, 2024
Status verified
Mar 2025
Primary completion
Mar 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
100 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: AIH Group
    Participants will be exposed to 4 consecutive days of acute intermittent hypoxia (AIH): 15, 1.5 min episodes at 9% O2 alternating with 21% O2 at 1 min intervals.
  • No Intervention: SHAM Group
    Participants will be exposed to 4 consecutive days of normoxia: 15, 1.5 min episodes at 21% O2 alternating with 21% O2 at 1 min intervals.

Primary Outcome Measure

Change in Serum Blood Brain Derived Neurotrophic Factor [ Time Frame: Baseline, Day 1, Day 3, and Day 4 ]

Locations (1)

FacilityCityStateZIPSite coordinators
Andrew TanBoulderColorado80309-

Find similar trials in Boulder, CO

By research site
Andrew Tan· Boulder, CO

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