Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Part of paid clinical trials in Worcester, Massachusetts.

Sponsor
Ningcheng Peter Li
Study ID
NCT06888024
Status
Recruiting
Apply to this trial

Conditions

  • Iliac Venous Compression
  • May-Thurner Syndrome

Eligibility Criteria

Sex
ALL
Age
18 Years - 89 Years
Healthy Volunteers
Accepted

Interventions

  • non-contrast enhanced abdomen and pelvis MRI — PROCEDURE
    non-contrast enhanced abdomen and pelvis MRI

Study Details

The purpose of the study is to quantitatively characterize the flow in the pelvic venous structures using 2D and 4D flow MRI with the objective of establishing physiologic and pathologic parameters for downstream computational fluid dynamics analysis. Arm 1: To establish the baseline flow characteristics of the iliac veins in patients with no imaging evidence of iliac venous disease. Arm 2: To assess the flow characteristics of the iliac veins in patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome). Arm 3: To assess the flow characteristics of the iliac veins in patients status post iliac stent placement.

Key Dates

Start date
Apr 1, 2025
Status verified
Sep 2025
Primary completion
Jan 1, 2027
Completion
Jan 1, 2027

Study Design

Enrollment
15 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Patients with no imaging evidence of iliac venous disease
    Healthy volunteers with no self-reported history or prior imaging evidence of pelvic venous disease or associated symptoms to undergo 2D and 4D flow MRI without contrast administration
  • Experimental: Patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome).
    Patients with prior imaging evidence of left common iliac vein compression syndrome to undergo 2D and 4D flow MRI without contrast administration
  • Experimental: Patients status post iliac stent placement
    Patients with a history of iliac stent placement to undergo 2D and 4D flow MRI without contrast administration

Primary Outcome Measure

Flow Volume [ Time Frame: At Enrollment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MassachusettsWorcesterMassachusetts01655
Noelle Bodkin
[email protected]
774-441-8442

Find similar trials in Worcester, MA

By research site
University of Massachusetts· Worcester, MA

Related Studies