Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD

Part of paid clinical trials in Fargo, North Dakota.

Sponsor
Sanford Health
Study ID
NCT06883266
Status
Recruiting
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Conditions

  • Parkinsons Disease (PD)

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Interventions

  • transcranial direct current stimulation (tDCS) — DEVICE
    2 mA will be administered for 5 consecutive days for a duration of 20 minutes with electrode placement at the left dorsolateral prefrontal cortex.
  • Sham (No Treatment) — DEVICE
    For 30 seconds, the patient will experience a ramp up of the stimulation, after which point no stimulation will be transmitted for the remainder of the session. This will be administered for 5 consecutive days for a duration of 20 minutes with electrode placement at the left dorsolateral prefrontal cortex

Study Details

The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left primary motor cortex (M1) will induce long-lasting effects in improving motor function and reducing motor fatigue and fatigability in PD patients.

Key Dates

Start date
Nov 11, 2024
Status verified
Jan 2026
Primary completion
Nov 11, 2026
Completion
Dec 11, 2026

Study Design

Enrollment
64 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Experimental Group
    The experimental group will receive 2mA of anodal transcranial direct current stimulation (tDCS) for 20 minutes daily for 5 consecutive days.
  • Sham Comparator: Sham Group
    The sham group will be connected to the anodal transcranial direct current stimulation device daily for 5 days. During the 20 minute sessions, the participant will only receive stimulation for a 30-second ramp up period, at which point the stimulation will be discontinued for the remainder of the time.

Primary Outcome Measure

Finger and Toe-Tapping on KinesiaOne Device [ Time Frame: 30 minutes; pre-test during the second research visit, post-test on 6th research visit after 5 consecutive days of tDCS, a follow up test on the 7th research visit, 7 days after last tDCS session and 8th visit 14 days after last tDCS session ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Sanford Brain and Spine CenterFargoNorth Dakota58103
Jessica Keller, B.S.
[email protected]
701-417-5781
Jau-Shin Lou, MD (PRINCIPAL_INVESTIGATOR)

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By research site
Sanford Brain and Spine Center· Fargo, ND

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