Effect of Snacks on Aging
Part of paid clinical trials in Los Angeles, California.
- Sponsor
- University of California, Los Angeles
- Study ID
- NCT06879626
- Status
- Recruiting
Conditions
- Aging
Eligibility Criteria
- Sex
- FEMALE
- Age
- 55 Years - 75 Years
- Healthy Volunteers
- Accepted
Interventions
- Pecan — OTHER2 oz of whole raw pecans
- Pretzel — OTHER3.5 oz of pretzel snacks daily
Study Details
The purpose of this study is to determine if daily consumption of 2 oz of pecans compared to 3.5 oz pretzel snacks for 12 weeks will 1) contribute to the body's ability to protect itself from oxidative damage (caused by oxygen radicals created by ultraviolet (UV) B light) by evaluating skin resistance to UV light irritation, skin fats/oils degradation and "rusting", and oxidative damage to the skin genes; and 2) explore the mechanisms of how snack consumption may affect aging by analyzing blood markers of aging as well as the microbes living in the gut (gut microbiome).
Key Dates
- Start date
- May 19, 2025
- Status verified
- May 2025
- Primary completion
- Jun 30, 2026
- Completion
- Jun 30, 2026
Study Design
- Enrollment
- 60 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- PREVENTION
Arms
- Experimental: Pecan armParticipats in this arm will be comsuming 2 oz of pecans daily for 12 wekks
- Experimental: Pretzel armParticipants in this arm will consume 3.5 oz of pretzel snacks daily for 12 weeks
Primary Outcome Measure
Minimal Erythema Dose (MED) [ Time Frame: At baseline and 12 weeks ]
Central Contacts
- Tatiana Diacova, PhD, RD310-206-8292
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| UCLA Center for Human Nutrition | Los Angeles | California | 90095 | Zhaoping Li, MD, PhD (PRINCIPAL_INVESTIGATOR) |
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