Effect of Snacks on Aging

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT06879626
Status
Recruiting

Conditions

  • Aging

Eligibility Criteria

Sex
FEMALE
Age
55 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Pecan — OTHER
    2 oz of whole raw pecans
  • Pretzel — OTHER
    3.5 oz of pretzel snacks daily

Study Details

The purpose of this study is to determine if daily consumption of 2 oz of pecans compared to 3.5 oz pretzel snacks for 12 weeks will 1) contribute to the body's ability to protect itself from oxidative damage (caused by oxygen radicals created by ultraviolet (UV) B light) by evaluating skin resistance to UV light irritation, skin fats/oils degradation and "rusting", and oxidative damage to the skin genes; and 2) explore the mechanisms of how snack consumption may affect aging by analyzing blood markers of aging as well as the microbes living in the gut (gut microbiome).

Key Dates

Start date
May 19, 2025
Status verified
May 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Pecan arm
    Participats in this arm will be comsuming 2 oz of pecans daily for 12 wekks
  • Experimental: Pretzel arm
    Participants in this arm will consume 3.5 oz of pretzel snacks daily for 12 weeks

Primary Outcome Measure

Minimal Erythema Dose (MED) [ Time Frame: At baseline and 12 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UCLA Center for Human NutritionLos AngelesCalifornia90095
Tatiana Diacova, PhD, RD
310-206-8292
Zhaoping Li, MD, PhD (PRINCIPAL_INVESTIGATOR)

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