Endosonographic Shear Wave Elastography to Assess Liver and Splenic Fibrosis

Part of paid clinical trials in Spokane, Washington.

Sponsor
Providence Medical Research Center
Study ID
NCT06867731
Status
Enrolling By Invitation

Conditions

  • Cirrhosis
  • Liver Fibrosis

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Endosonographic Elastography — PROCEDURE
    The patient will undergo a standard-of-care endoscopic ultrasound with liver biopsy. At the time, elastography of the liver and spleen will be performed while using the echoendoscope. Different degrees of pressure will be applied while performing elastography of the left and right lobes of the liver as well as the spleen. The E values and VsN values will be recorded and then compared to liver histology.
  • Endosonographic shear wave elastography — DIAGNOSTIC_TEST
    The patient will undergo an upper endoscopic ultrasound procedure. During this procedure, the patient will be put to sleep and a trained endosonographer physician will insert an echo-endoscope through the mouth and guide it down to the stomach and the duodenum. This endoscope is equipped with technology that uses sound waves to assess the stiffness of the liver and spleen. For research purposes, the doctor will also press on these organs in order to take the additional measurements.

Study Details

The study is being done to collect information on the effectiveness of endosonographic elastography (a technique which uses sound waves) to measure the stiffness of the liver and spleen. Investigators are trying to determine if shear wave elastography is a good way to measure fibrosis instead of biopsy.

Key Dates

Start date
Jan 30, 2025
Status verified
May 2025
Primary completion
Jan 30, 2026
Completion
Jan 30, 2027

Study Design

Enrollment
120 participants (estimated)

Arms

  • Arm: Elastography
    Diagnostic test: Endosonographic shear wave elastography

Primary Outcome Measure

Degree of fibrosis [ Time Frame: Enrollment to 4 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
Providence Sacred Heart Medical CenterSpokaneWashington99204-

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By research site
Providence Sacred Heart Medical Center· Spokane, WA

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