Well-being in IBS: Strengths and Happiness (WISH) 2.0

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT06866106
Status
Recruiting
Apply to this trial

Conditions

  • Irritable Bowel Syndrome

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Positive Psychology (PP) Intervention — BEHAVIORAL
    This is an adapted, optimized, phone-based, 9-week positive psychology (PP) intervention. Participants will complete 9 weekly phone sessions (30 minutes each) with a study interventionist in which they will review PP exercises that they have independently completed in between phone sessions. The PP exercises will be completed in a treatment manual that describes the PP exercise and provides space to write about the exercise and its effects, and to answer associated questions. A total of 9 sessions will be completed over the course of the program.
  • Educational Intervention — BEHAVIORAL
    This is an educational intervention that will match the PP intervention in terms of both time and attention. Participants will complete 9 weekly phone sessions (30 minutes each) with a study interventionist in which they will review educational exercises that they have independently completed in between phone sessions. The exercises will be completed in a treatment manual that describes the exercise and provides space to write about the exercise and its effects, and to answer associated questions. A total of 9 sessions will be completed over the course of the program.

Study Details

The purpose of this study is to examine the feasibility, acceptability, preliminary effects, and candidate gut-brain mechanisms of an optimized positive psychology (PP) intervention for patients with irritable bowel syndrome (IBS), entitled "WISH," compared to an educational control intervention.

Key Dates

Start date
Oct 30, 2025
Status verified
Apr 2026
Primary completion
Apr 30, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Positive Psychology (PP) Intervention
    Participants will complete an adapted, optimized, phone-based, 9-week positive psychology (PP) intervention.
  • Active Comparator: Educational Intervention
    Participants will complete a 9-week, phone-based educational intervention that matches the PP intervention in terms of both time and attention.

Primary Outcome Measure

Proportion of Intervention Sessions Completed by Participants [ Time Frame: Post-intervention at 9 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts General HospitalBostonMassachusetts02114
Elizabeth N Madva, MD
[email protected]
617-724-6300

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By research site
Massachusetts General Hospital· Boston, MA

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