Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis
Part of paid clinical trials in Cleveland, Ohio.
- Sponsor
- The Cleveland Clinic
- Study ID
- NCT06857240
- Phase
- PHASE2
- Status
- Recruiting
Conditions
- Dermatomyositis
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 89 Years
- Healthy Volunteers
- Not accepted
Interventions
- Ruxolitinib Topical Cream — DRUG1.5% cream
Study Details
This study will assess the safety and efficacy of topical ruxolitinib for treating the refractory cutaneous manifestations in patients with dermatomyositis. The investigators' hypothesis is that topical ruxolitinib will be both safe and effective for such patients.
Key Dates
- Start date
- Jun 1, 2025
- Status verified
- Jul 2025
- Primary completion
- Dec 31, 2026
- Completion
- Dec 31, 2027
Study Design
- Enrollment
- 15 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: Treatment1.5 % Ruxolitinib cream
Primary Outcome Measure
CDASI [ Time Frame: 8 weeks ]
Central Contacts
- Anthony Fernandez, MD216 445-8776
- Rothy Rim2164447277
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Cleveland Clinic | Cleveland | Ohio | 44195 | Anthony Fernandez, MD |
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