Psilocybin-Assisted Therapy for Physician Well-Being and Burnout

Part of paid clinical trials in San Diego, California.

Sponsor
University of California, San Diego
Study ID
NCT06814522
Phase
PHASE1/PHASE2
Status
Recruiting

Conditions

  • Burnout
  • Burnout, Healthcare Workers

Eligibility Criteria

Sex
ALL
Age
21 Years - 70 Years
Healthy Volunteers
Not accepted

Interventions

  • Psilocybin, [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate — DRUG
    25 mg, single dose of psilocybin

Study Details

Through an open-label study involving a small group of UCSD physicians experiencing burnout, the investigators will evaluate the feasibility, safety, and preliminary effectiveness of PAT to reduce burnout symptoms.

Key Dates

Start date
Jan 13, 2025
Status verified
Nov 2025
Primary completion
Jun 30, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Psilocybin-Assisted Therapy
    Subjects will receive a single dose of psilocybin in conjunction with psychedelic-assisted therapy.

Primary Outcome Measure

Stanford Professional Fulfillment Index (PFI) [ Time Frame: From enrollment until end of study at 12 week follow-up. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UC San DiegoSan DiegoCalifornia92037
Jessie Kim
619-494-0037
Cory R Weissman, MD, PhD (PRINCIPAL_INVESTIGATOR)

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