Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds

Part of paid clinical trials in Lebanon, New Hampshire.

Sponsor
Dartmouth-Hitchcock Medical Center
Study ID
NCT06792474
Phase
PHASE4
Status
Not Yet Recruiting

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Conditions

  • Anesthesia
  • Post Operative Pain
  • Spinal Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Lidocaine in Saline — DRUG
    Lidocaine infusion 1.5 mg/kg/hr
  • Normal saline — DRUG
    Normal saline infusion

Study Details

The purpose of this study is to determine the effect of lidocaine infusion on intraoperative neuromonitoring in patients undergoing spine surgery.

Key Dates

Start date
Aug 31, 2026
Status verified
Nov 2025
Primary completion
Aug 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
44 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Lidocaine Infusion (Active)
    Lidocaine infusion
  • Sham Comparator: Normal Saline Infusion (Sham)
    Normal saline infusion

Primary Outcome Measure

Motor Evoked Potentials (MEPs) [ Time Frame: Duration of the surgical procedure, no more than 24 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Dartmouth Hitchcock Medical CenterLebanonNew Hampshire03766
Lauren Buhl, MD, PhD
[email protected]
603-650-5000

Find similar trials in Lebanon, NH

By research site
Dartmouth Hitchcock Medical Center· Lebanon, NH

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