Working Memory Training in Patients with Mild Cognitive Impairment

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Study ID
NCT06734286
Status
Recruiting
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Conditions

  • Mild Cognitive Impairment (MCI)

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • CogMed — OTHER
    CogMed which is a computerized working memory training program developed by Karolinska University.

Study Details

The purpose of this study is to test whether a special memory training program, called CogMed, can help people with early memory problems. The Investigators want to see if this training improves memory and also helps reduce stress. The Investigators also want to see if CogMed results in changes to a blood biomarker called p-Tau 217, which possibly indicate Alzheimer's disease (AD).

Key Dates

Start date
Sep 16, 2024
Status verified
Nov 2024
Primary completion
Jun 30, 2025
Completion
Sep 30, 2025

Study Design

Enrollment
10 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Intervention Group
    The Intervention Group (N = 5) Participants will be instructed to do CogMed intervention (computerized working memory activity carried out for 25 minutes daily for 5 days per week for a total of 10 weeks).
  • No Intervention: Control Group
    The Control group(N = 5) follow there Treatment as usual(TAU). For ethical reasons, at the end of trial, the control group will also be offered the CogMed intervention.

Primary Outcome Measure

Working Memory as measured by the WAIS-IV Digit Span Forward/Backward [ Time Frame: Will be assessed at baseline and again at a 3-month follow-up following the intervention period. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Barrow Neurological Institute, Division of Alzheimer's DiseasePhoenixArizona85013
Yonas E Geda, M.D, MSc
[email protected]
833-233-3073
Geetika Chahal, MBBS
[email protected]
602-406-7240

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By research site
Barrow Neurological Institute, Division of Alzheimer's Disease· Phoenix, AZ

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