A Study of Lung Cancer Screening in People With Unexplained Weight Loss
Part of paid clinical trials in Basking Ridge, New Jersey.
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Study ID
- NCT06717334
- Status
- Recruiting
Conditions
- Lung Cancer Screening
Eligibility Criteria
- Sex
- ALL
- Age
- 50 Years - 80 Years
- Healthy Volunteers
- Accepted
Interventions
- Low Dose CT imaging — DIAGNOSTIC_TESTat baseline and at Year 1.
- blood draws — OTHERat baseline and at Year 1.
- screening questionnaire — OTHERat baseline and at 1 year after registration.
Study Details
The researchers are doing this study to see if people with unexplained weight loss who have lung cancer screening are more likely to have or develop lung cancer than people without unexplained weight loss. The lung cancer screening will involve use of low-dose computed tomography (LDCT), a CT scan that gives off very low doses of radiation and can make detailed pictures of the lungs to help find tumors. The study researchers will also analyze participants' blood samples to determine if blood testing can be used to help to diagnose lung cancer.
Key Dates
- Start date
- Dec 2, 2024
- Status verified
- Jan 2026
- Primary completion
- Dec 31, 2026
- Completion
- Dec 31, 2026
Study Design
- Enrollment
- 409 participants (estimated)
Arms
- Arm: Patients undergoing Lung cancer screeningAll patients will undergo prospective LDCT imaging annually. At baseline and Year 1, patients will also undergo biospecimen collection for post-hoc ctDNA analysis.
Primary Outcome Measure
The incidence of lung cancer in patients with unexplained weight loss [ Time Frame: 2 years ]
Central Contacts
- Puneeth Iyengar, MD, PhD212-639-5159
- Bernard Park, MD646-888-3346
Locations (8)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Memorial Sloan Kettering at Basking Ridge (All Protocol Activities) | Basking Ridge | New Jersey | 07920 | Puneeth Iyengar, MD, PhD 212-639-5159 |
| Memorial Sloan Kettering Monmouth (All Protocol Activities) | Middletown | New Jersey | 07748 | Puneeth Iyengar, MD, PhD 212-639-5159 |
| Memorial Sloan Kettering Bergen (All Protocol Activities) | Montvale | New Jersey | 07645 | Puneeth Iyengar, MD, PhD 212-639-5159 |
| Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities) | Commack | New York | 11725 | Puneeth Iyengar, MD, PhD 212-639-5159 |
| Memorial Sloan Kettering Westchester (All Protocol Activities) | Harrison | New York | 10604 | Puneeth Iyengar, MD, PhD 212-639-5159 |
| Memorial Sloan Kettering Cancer Center (All Protocol Activities) | New York | New York | 10065 | Puneeth Iyengar, MD, PhD 212-639-5159 |
| Montefiore Health Systems (Montefiore Medical Center) | The Bronx | New York | 10467 | Neel Chudgar, MD 718-920-8874 |
| Memorial Sloan Kettering Nassau (All Protocol Activities) | Uniondale | New York | 11553 | Puneeth Iyengar, MD, PhD 212-639-5159 |
Find similar trials in Basking Ridge, NJ
By research site
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (All Protocol Activities)· Middletown, NJMemorial Sloan Kettering Bergen (All Protocol Activities)· Montvale, NJMemorial Sloan Kettering Suffolk-Commack (All Protocol Activities)· Commack, NYMemorial Sloan Kettering Westchester (All Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY
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