A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors

Part of paid clinical trials in Irvine, California.

Sponsor
Bristol-Myers Squibb
Study ID
NCT06697197
Phase
PHASE1/PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Advanced Solid Tumors

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of this study is to test the safety and efficacy of BMS-986482 alone and as combination therapy in participants with advanced solid tumors.

Key Dates

Start date
Feb 17, 2025
Status verified
Jan 2026
Primary completion
Jan 4, 2029
Completion
Jan 5, 2029

Study Design

Enrollment
413 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Part 1A
  • Experimental: Part 1B1
  • Experimental: Part 1B2
  • Experimental: Part 1B3
  • Experimental: Part 1C
  • Experimental: Part 2A
  • Experimental: Part 2B1
  • Experimental: Part 2B2
  • Experimental: Part 2B3

Primary Outcome Measure

Number of participants with Adverse Events (AEs) as assessed by National Cancer Institute -Common Terminology Criteria for Adverse Events version 5.0 (NCI-CTCAE v5.0) [ Time Frame: Up to 135 days post last treatment visit ]

Central Contacts

  • BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
    855-907-3286
    [email protected]
  • First line of the email MUST contain NCT # and Site #.

Locations (7)

FacilityCityStateZIPSite coordinators
University of California, Irvine (UCI) Health - UC Irvine Medical CenterIrvineCalifornia92612
Warren Chow, Site 0005
626-372-7121
The Angeles Clinic and Research Institute - West Los Angeles OfficeLos AngelesCalifornia90025
Omid Hamid, Site 0030
310-231-2121
Local Institution - 0008AuroraColorado80045
Site 0008
John Theurer Cancer Center at Hackensack University Medical CenterHackensackNew Jersey07601
Martin Gutierrez, Site 0009
551-996-5863
Northwell Health/ RJ Zuckerberg Cancer CenterLake SuccessNew York11042
Nagashree Seetharamu, Site 0007
917-574-8494
Levine Cancer InstituteCharlotteNorth Carolina28204
Asim Amin, Site 0011
980-442-2000
Fred Hutchinson Cancer CenterSeattleWashington98109
Cristina Rodriguez, Site 0010
206-288-6748

Find similar trials in Irvine, CA

By research site
University of California, Irvine (UCI) Health - UC Irvine Medical Center· Irvine, CAThe Angeles Clinic and Research Institute - West Los Angeles Office· Los Angeles, CALocal Institution - 0008· Aurora, COJohn Theurer Cancer Center at Hackensack University Medical Center· Hackensack, NJNorthwell Health/ RJ Zuckerberg Cancer Center· Lake Success, NYLevine Cancer Institute· Charlotte, NC

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