A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity

Part of paid clinical trials in Tempe, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT06662383
Phase
PHASE3
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The main purpose of this study is to evaluate the efficacy and safety of retatrutide compared to tirzepatide in adults who have obesity. The study will last about 89 weeks.

Key Dates

Start date
Nov 1, 2024
Status verified
Apr 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
800 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Retatrutide
    Participants will receive retatrutide administered subcutaneously (SC)
  • Active Comparator: Tirzepatide
    Participants will receive tirzepatide administered SC

Primary Outcome Measure

Percent Change from Baseline in Body Weight [ Time Frame: Baseline, Week 80 ]

Locations (40)

FacilityCityStateZIPSite coordinators
Medical Advancement Centers of ArizonaTempeArizona85283-
Mary & Dick Allen Diabetes CenterNewport BeachCalifornia92663-
Artemis Institute for Clinical ResearchSan DiegoCalifornia92103-
Encompass Clinical ResearchSpring ValleyCalifornia91978-
Diablo Clinical Research, Inc.Walnut CreekCalifornia94598-
Lynn Institute of DenverAuroraColorado80012-
Bridgeport HospitalBridgeportConnecticut06610-
Yale University School of MedicineNew HavenConnecticut06519-
Encore Medical ResearchHollywoodFlorida33024-
Onhealth Research CenterMiamiFlorida33186-
Suncoast Research GroupMiamiFlorida33135-
Precision Clinical ResearchSunriseFlorida33351-
Einstein Clinical ResearchVero BeachFlorida32960-
ClinCept Clinical Research - MHColumbusGeorgia31904-
Northeast Georgia Medical CenterGainesvilleGeorgia30501-
Pivotal Research SolutionsStonecrestGeorgia30038-
East-West Medical Research InstituteHonoluluHawaii96814-
Northwestern UniversityChicagoIllinois60611-
Integrated Clinical Trial Services, Inc.West Des MoinesIowa50265-
Pennington Biomedical Research CenterBaton RougeLouisiana70808-
Great Lakes Research Group, Inc.Bay CityMichigan48706-
Great Lakes Research InstituteSouthfieldMichigan48075-
StudyMetrix ResearchCity of Saint PetersMissouri63303-
Las Vegas EndocrinologyHendersonNevada89074-
Albany Medical College, Division of Community EndocrinologyAlbanyNew York12203-
New York Gastroenterology AssociatesNew YorkNew York10075-
Westchester Medical CenterValhallaNew York10595-
PharmQuest Life Sciences, LLCGreensboroNorth Carolina27408-
Monroe Biomedical ResearchMonroeNorth Carolina28112-
Accellacare - WilmingtonWilmingtonNorth Carolina28401-
Lillestol ResearchFargoNorth Dakota58104-
PriMED Clinical ResearchDaytonOhio45429-
Tribe Clinical Research, LLCGreenvilleSouth Carolina29607-
WR-Clinsearch, LLCChattanoogaTennessee37421-
Headlands Horizons LLCBrownsvilleTexas78526-
Houston Research InstituteHoustonTexas77079-
Next Level Urgent CareHoustonTexas77057-
Consano Clinical Research, LLCShavano ParkTexas78231-
Chrysalis Clinical ResearchSt. GeorgeUtah84790-
Charlottesville Medical ResearchCharlottesvilleVirginia22911-

Find similar trials in Tempe, AZ

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Medical Advancement Centers of Arizona· Tempe, AZMary & Dick Allen Diabetes Center· Newport Beach, CAArtemis Institute for Clinical Research· San Diego, CAEncompass Clinical Research· Spring Valley, CADiablo Clinical Research, Inc.· Walnut Creek, CALynn Institute of Denver· Aurora, CO

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