PKP2-ACM Natural History Study

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Rocket Pharmaceuticals Inc.
Study ID
NCT06644742
Status
Recruiting
Apply to this trial

Conditions

  • Cardiomyopathies
  • Cardiovascular Diseases
  • Genetic Diseases
  • Heart Diseases

Eligibility Criteria

Sex
ALL
Age
12 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The goal of this study is to describe the natural history and clinical events for patients who have Arrhythmogenic Cardiomyopathy with Pathogenic Plakophilin-2 Variants (PKP2-ACM) managed with standard of care.

Key Dates

Start date
Mar 31, 2026
Status verified
Feb 2026
Primary completion
Dec 31, 2030
Completion
Apr 30, 2031

Study Design

Enrollment
36 participants (estimated)

Arms

  • Arm: Prospective and Retrospective Cohort (No Intervention)

Primary Outcome Measure

Heart rhythm and rate monitoring measures [ Time Frame: 36 months ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02116
Dominic Abrams, MD
[email protected]
617 355-6955
Dominic Abrams, MD (PRINCIPAL_INVESTIGATOR)
Duke UniversityDurhamNorth Carolina27710
James Daubert, MD
[email protected]
919-681-4294
James Daubert, MD (PRINCIPAL_INVESTIGATOR)

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Boston Children's Hospital· Boston, MADuke University· Durham, NC

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