Using PrEP, Doing It for Ourselves

Part of paid clinical trials in Durham, North Carolina.

Sponsor
Duke University
Study ID
NCT06638892
Status
Recruiting
Apply to this trial

Conditions

  • HIV Prevention
  • PrEP

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Using PrEP, Doing it for Ourselves (UPDOs) — BEHAVIORAL
    An e-Health intervention that considers women's lived experiences and uses three components: beauty salons and stylists as opinion leaders (trusted gatekeepers who share health information in the community), theory driven edutainment videos and blogs, and a secure online platform for accessing pre-exposure prophylaxis (PrEP).
  • Standard of Care — OTHER
    CDC standard of care, e.g., CDC videos and website.

Study Details

The goal of this clinical trial is to test a new online program called UPDOs Protective Styles to help people in the southeastern United States learn about and start using PrEP (pre-exposure prophylaxis), a medicine that helps prevent HIV. The study focuses on people who may be at higher risk for HIV and have not had equal access to PrEP. The main questions it aims to answer are: Does UPDOs help more people trust and understand PrEP? Does UPDOs increase the number of people who start and continue using PrEP? Researchers will compare two groups: One group will use UPDOs, which includes six weekly videos, blog discussions, and access to telehealth services through Q Care Plus. The other group will receive standard HIV prevention materials from the CDC. Participants will: Be recruited from 32 beauty salons in areas with high HIV rates. Complete surveys at the start of the study and again at 6, 12, 24, 32, and 52 weeks. Have access to HIV testing and PrEP prescriptions through Q Care Plus. This study will also look at how well the program works in different communities and how easy it is to use and share.

Key Dates

Start date
Feb 13, 2026
Status verified
Feb 2026
Primary completion
Jun 30, 2029
Completion
Jan 31, 2030

Study Design

Enrollment
1,000 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Using PrEP, Doing it for Ourselves (UPDOs) intervention
    This group will receive the UPDOs intervention that includes "edutainment", e.g., videos, blogs, vlogs, and Q Care Plus.
  • Other: Standard of Care
    This group will receive CDC standard of care, e.g., CDC videos and website.

Primary Outcome Measure

Pre-exposure prophylaxis (PrEP) Contemplation Ladder total score [ Time Frame: 12 weeks post-intervention ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Duke University School of NursingDurhamNorth Carolina27710
Niasha Fray, MA, MSPH
[email protected]
9196688325
Schenita Randolph, PhD, MPH, RN, FAAN (PRINCIPAL_INVESTIGATOR)
Ragan Johnson, DNP, FNP-BC, CNE, FAANP (SUB_INVESTIGATOR)
Michael Relf, PhD, RN, ANEF, FAAN (SUB_INVESTIGATOR)
Hannah Lane, PhD (SUB_INVESTIGATOR)

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By research site
Duke University School of Nursing· Durham, NC

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