Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation

Part of paid clinical trials in Milwaukee, Wisconsin.

Sponsor
Marquette University
Study ID
NCT06624982
Status
Recruiting
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Conditions

  • Alveolar Bone Grafting
  • Bone Healing
  • Tooth Extraction Site Healing
  • Wound Healing

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • observational study — OTHER
    Observational study; alveolar ridge preservation

Study Details

The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width condition (expansion or no change) is a determinant of buccolingual ridge width and height changes 4 months following extraction and ridge preservation.

Key Dates

Start date
Oct 8, 2025
Status verified
Nov 2025
Primary completion
Oct 1, 2027
Completion
Oct 1, 2027

Study Design

Enrollment
160 participants (estimated)

Arms

  • Arm: Non-molar sites with immediate post-extraction ridge expansion
    Non-molar sites with an increase of buccolingual bone width immediately after tooth extraction compared to pre-extraction.
  • Arm: Non-molar sites with no immediate post-extraction ridge width change
    Non-molar sites without a change in buccolingual bone width immediately after tooth extraction compared to pre-extraction.
  • Arm: Molar sites with immediate post-extraction ridge expansion
    Molar sites with an increase of buccolingual bone width immediately after tooth extraction compared to pre-extraction.
  • Arm: Molar sites with no immediate post-extraction ridge width change
    Molar sites without a change in buccolingual bone width immediately after tooth extraction compared to pre-extraction.

Primary Outcome Measure

Buccolingual ridge width [ Time Frame: (1) After local anesthesia and before extraction, (2) immediately after extraction and (3) 4 months after extraction and alveolar ridge preservation ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Marquette University School of Dentistry Graduate Periodontics ClinicMilwaukeeWisconsin53233
Vrisiis Kofina, DDS, MS
[email protected]
4142886521
Arndt Guentsch, DMD, PhD, MHBA, MS
[email protected]
4142886089
Vrisiis Kofina, DDS, MS (PRINCIPAL_INVESTIGATOR)

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By research site
Marquette University School of Dentistry Graduate Periodontics Clinic· Milwaukee, WI

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