AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

Part of paid clinical trials in Durham, North Carolina.

Sponsor
Duke University
Study ID
NCT06619405
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 89 Years
Healthy Volunteers
Accepted

Interventions

  • Streetlab VR — DIAGNOSTIC_TEST
    Streetlab VR is a virtual reality headset that is warn to simulate walking through a maze at different light levels.

Study Details

The goal is to conduct a cross-sectional, single timepoint study on older adults with early and intermediate AMD, and with subretinal drusenoid deposits (SDD), and those in normal health, establishing an association between dark adaptation and reading performance under dim illumination, both which depend on rod photoreceptors.

Key Dates

Start date
Aug 15, 2025
Status verified
Aug 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Other: Early AMD
    Study patients who have a diagnosis of early AMD
  • Other: Intermediate AMD
    Study patients who have a diagnosis of Intermediate AMD
  • Other: Geographic Atrophy
    Study patients who have a diagnosis of Geographic Atrophy
  • Other: AMD Controls
    Study patients who have healthy eyes

Primary Outcome Measure

Total number of participants with total ellipsoid zone (EZ) band attenuation [ Time Frame: Approximately 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Duke Eye CenterDurhamNorth Carolina27710-

Find similar trials in Durham, NC

By condition
Age-related macular degeneration
By specialty
OphthalmologyRetina
By research site
Duke Eye Center· Durham, NC

Related Studies