Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Part of paid clinical trials in Miami, Florida.

Sponsor
University of Miami
Study ID
NCT06578156
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Nasal High Flow Cannula — DEVICE
    High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
  • Nasal Low Flow Cannula — DEVICE
    Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times

Study Details

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Key Dates

Start date
Dec 12, 2024
Status verified
Apr 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Nasal High Flow Cannula
    Nasal High Flow cannula at 70 liters per minute for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to Nasal Low Flow Cannula at less than or equal to 4 liters per minute with supplemental oxygen for 30 minutes
  • Active Comparator: Nasal Low Flow Cannula
    Low Flow Nasal Cannula at less than or equal to 4 liters per minute with supplemental oxygen at patient's baseline for 30 minutes. Given that this is a cross-over study, participants on this arm will be then crossed over to High Flow Cannula at 70 liters per minute for 30 minutes

Primary Outcome Measure

6-minute walk test [ Time Frame: 30 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MiamiMiamiFlorida33136
Saramaria Afanador Castiblanco, M.D.
[email protected]
3052432568
Saramaria Afanador Castiblanco, M.D. (PRINCIPAL_INVESTIGATOR)

Find similar trials in Miami, FL

By condition
COPD
By specialty
PulmonologyLung disease
By research site
University of Miami· Miami, FL

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