The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles

Part of paid clinical trials in Sacramento, California.

Sponsor
Integrative Skin Science and Research
Study ID
NCT06571721
Status
Recruiting
Apply to this trial

Conditions

  • Collagen Degeneration
  • Elastic Skin
  • Pigmentation
  • Sebum Deficiency
  • Wrinkle

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Topical Product: Almond Oil — OTHER
    1-2 Drops of randomized topical product will be applied on entire face nightly.
  • Topical Product: Almond oil augmented with 0.5% Vitamin E — OTHER
    1-2 Drops of randomized topical product will be applied on entire face nightly.
  • Topical Product: 0.025% Tretinoin oil augmented with castor oil — OTHER
    1-2 Drops of randomized topical product will be applied on entire face nightly.

Study Details

Investigate the topical use of almond oil, almond oil augmented with 0.5% vitamin E, 0.025% tretinoin oil augmented with castor oil on the appearance of facial fine lines and wrinkles, pigmentation, hydration, trans-epidermal water loss, and sebum excretion rate.

Key Dates

Start date
Jul 22, 2024
Status verified
Aug 2024
Primary completion
Jan 22, 2025
Completion
Jul 22, 2025

Study Design

Enrollment
90 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Almond Oil
    Almond Oil. 1-2 Drops of randomized topical product will be applied on entire face nightly. Duration: 16 weeks
  • Experimental: Almond oil augmented with 0.5% Vitamin E
    Almond oil augmented with 0.5% Vitamin E. 1-2 Drops of randomized topical product will be applied on entire face nightly. Duration: 16 weeks
  • Experimental: 0.025% Tretinoin oil augmented with castor oil
    0.025% Tretinoin oil augmented with castor oil. 1-2 Drops of randomized topical product will be applied on entire face nightly. Duration: 16 weeks

Primary Outcome Measure

Facial wrinkles [ Time Frame: 16 Weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Integrative Research InstituteSacramentoCalifornia95819
Nasima Afzal
[email protected]
915-750-2463
Sarah Adnan
[email protected]
9157502463
Raja Sivamani, MD (PRINCIPAL_INVESTIGATOR)
Rubaina Dang, ND (SUB_INVESTIGATOR)

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Integrative Research Institute· Sacramento, CA

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