fMRI Accelerated TMS Depression

Part of paid clinical trials in Charleston, South Carolina.

Sponsor
Medical University of South Carolina
Study ID
NCT06562153
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Neuroimaging with Magnetic Resonance Imaging (MRI) — OTHER
    MRI will be used to observe brain states over time.

Study Details

This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerated antidepressant transcranial magnetic stimulation (TMS) treatment.

Key Dates

Start date
Sep 23, 2024
Status verified
Oct 2025
Primary completion
Aug 5, 2026
Completion
Aug 5, 2026

Study Design

Enrollment
20 participants (estimated)

Arms

  • Arm: Volunteer Participants with Major Depressive Disorders (MDD)
    20 patients with MDD receiving 5-day accelerated transcranial magnetic stimulation therapy (TMS) from the clinic will be recruited to participate in this observational neuroimaging study. Participants will undergo two fMRI scans at baseline and post-treatment.

Primary Outcome Measure

Dynamic brain state change after 5-day transcranial magnetic stimulation (TMS) treatment compared to baseline [ Time Frame: 5 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
30 Bee StreetCharlestonSouth Carolina29429
Marion Wood
[email protected]
8437928502
Xiaolong Peng, Ph.D. (PRINCIPAL_INVESTIGATOR)

Find similar trials in Charleston, SC

By condition
Depression
By specialty
PsychiatryMental healthBehavioral health
By research site
30 Bee Street· Charleston, SC

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