Cardiovascular Health & Early Stress

Part of paid clinical trials in Richmond, Virginia.

Sponsor
Virginia Commonwealth University
Study ID
NCT06557707
Status
Recruiting
Apply to this trial

Conditions

  • Stress

Eligibility Criteria

Sex
ALL
Age
9 Years - 30 Years
Healthy Volunteers
Accepted

Interventions

  • Childhood stress — OTHER
    Based on stress-related information, participants will be divided into those who were exposed to adversity during childhood and those who were not exposed.

Study Details

Childhood adversity is highly prevalent, with 59% of the U.S. population reporting at least one adverse childhood experience (ACE). Substantial evidence links childhood adversity to cardiometabolic disease later in the life course, including heart disease, diabetes, and stroke, which are 3 of the top 10 causes of mortality in the United States. ACEs encompass many possible traumatic and distressing experiences, including abuse, neglect, or severe household dysfunctions. It is not surprising that the experience of those extreme events during the first decade of life has tremendous implications for the individual's psychological and physical health.

Key Dates

Start date
Jan 20, 2022
Status verified
Aug 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2028

Study Design

Enrollment
120 participants (estimated)

Arms

  • Arm: Young individuals ACE (ages 18-30 years old)
    Young individuals who experienced accumulative adverse childhood experiences
  • Arm: Children ACE (ages 9-17 years old)
    Children who experienced accumulative adverse childhood experiences .
  • Arm: Young individuals No ACE (ages 18-30 years old)
    Young individuals who have not experienced accumulative adverse childhood experiences
  • Arm: Children No ACE (ages 9-17 years old)
    Children who have not experienced accumulative adverse childhood experiences.

Primary Outcome Measure

Vascular function [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Virginia Commonwealth UniversityRichmondVirginia23298
Paula Rodriguez Miguelez
[email protected]
804-396-4498

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By research site
Virginia Commonwealth University· Richmond, VA

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