Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Massachusetts General Hospital
Study ID
NCT04496947
Status
Recruiting
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Conditions

  • Atherosclerosis
  • Inflammation
  • Stress

Eligibility Criteria

Sex
ALL
Age
30 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Stress Reduction — BEHAVIORAL
    The stress reduction program is a multimodal mind-body resiliency program that incorporates 3 core components into each session: * Elicitation of the Relaxation Response (RR) through mind-body techniques; * Discussion about stress awareness to learn how to identify personal stressors and experiences of stress; and * Coping strategies and adaptive perspective-taking to promote positive well-being.

Study Details

The plot study aims to evaluate the effect of 8 weeks of stress reducing intervention on atherosclerotic plaque inflammation in adults, as quantified by positron emission tomography (PET) with fluorine-2-deoxy-D-glucose (FDG) in individuals with increased psychosocial stress.

Key Dates

Start date
Sep 1, 2018
Status verified
Nov 2025
Primary completion
Jan 1, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Stress Reduction
    8 week stress reduction course
  • No Intervention: Control
    No intervention

Primary Outcome Measure

Change in arterial inflammation by PET [ Time Frame: 2 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Massachusetts General HospitalBostonMassachusetts02114
Ahmed Tawakol, MD
[email protected]
6177243699

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By research site
Massachusetts General Hospital· Boston, MA

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