Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

Part of paid clinical trials in Anchorage, Alaska.

Sponsor
Southcentral Foundation
Study ID
NCT06556238
Status
Recruiting
Apply to this trial

Conditions

  • Smoking Cessation

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Nicotine Metabolite Ratio — OTHER
    Blood specimens will be drawn, in clinic, by clinical staff trained in blood collection (e.g., certified medical assistant, nurse). Through regular clinic procedures, lab staff will ship for processing to Quest. Quest uses liquid chromatography tandem mass spectrometry with a limit of detection of 2ng/ml for all analytes and will quantify NMR within 3-6 days of sample arrival. Samples will be consumed during testing. Results of NMR will be returned to primary care providers, and NMR-informed medication recommendations will be made to participants.

Study Details

The purpose of this study is to refine and pilot an intervention using the Nicotine Metabolite Ratio (NMR) to inform the selection of pharmacologic treatment to increase smoking abstinence among Alaska Native and American Indian people. This is a single-arm pilot trial to assess and improve acceptability and feasibility.

Key Dates

Start date
Nov 17, 2025
Status verified
Apr 2026
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH

Arms

  • Experimental: Nicotine Metabolite Ratio
    Subjects identified as cigarette smokers wishing to quit will receive the Nicotine Metabolite Ratio (NMR) test in a primary care setting and the results of the NMR will be used to inform medication recommendations for tobacco cessation.

Primary Outcome Measure

Feasibility of intervention implementation: Enrollment [ Time Frame: Beta phase (n=10) 6 weeks; Pilot phase (n=40) 6 weeks, 12 weeks, 26 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Anchorage Native Primary Care CenterAnchorageAlaska99508
Georgia Michlig, PhD
[email protected]
907-729-5421

Find similar trials in Anchorage, AK

By research site
Anchorage Native Primary Care Center· Anchorage, AK

Related Studies