Analysis of Lung Cancer Tissue With Spatial Frequency Domain Imaging

Part of paid clinical trials in Orange, California.

Sponsor
University of California, Irvine
Study ID
NCT06549088
Status
Enrolling By Invitation

Conditions

  • Cancer, Lung
  • Lung Diseases

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Spatial Frequency Domain Imaging — DEVICE
    Resected lung tissue will be removed from the surgical field and labeled with sutures per standard of care. The specimen will then be immediately analyzed using two SFDI devices in the operating room using sterile technique. Each specimen will be recorded up to three times to ensure at least one high fidelity recording is captured. The SFDI data will be analyzed and compared to the official pathology report from the electronic medical record.

Study Details

This study investigates if a new imaging device can detect different types of lung tissue using spatial frequency domain imaging (SFDI). Specifically, this study aims to detect lung nodules within normal lung tissue and determine if lung nodules are cancerous. Patients who have confirmed or suspected lung nodules and who are undergoing resection of those nodules will be recruited for the study. Study participants will undergo standard of care lung nodule resection in the operating room, and the resected specimen will be imaged using the SFDI device immediately after removal from the surgical field. The data captured from the SFDI images will then be compared to the pathology findings to identify optical properties of normal and cancerous lung tissue. Because the intervention is conducted on resected biospecimens, this study yields minimal risk to participants.

Key Dates

Start date
Aug 7, 2023
Status verified
Aug 2024
Primary completion
Aug 1, 2025
Completion
Dec 31, 2026

Study Design

Enrollment
20 participants (estimated)

Primary Outcome Measure

Markers of native lung parenchyma [ Time Frame: May 7, 2023 to December 31, 2026 ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, Irvine Medical CenterOrangeCalifornia92868-

Find similar trials in Orange, CA

By research site
University of California, Irvine Medical Center· Orange, CA

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