Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Part of paid clinical trials in Worcester, Massachusetts.

Sponsor
University of Massachusetts, Worcester
Study ID
NCT06522880
Status
Recruiting
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Conditions

  • Cytomegalovirus Infections

Eligibility Criteria

Sex
ALL
Age
1 Day - 36 Months
Healthy Volunteers
Not accepted

Interventions

  • CMV PCR on saliva — DIAGNOSTIC_TEST
    Observational study to measure prevalence of CMV shedding by saliva PCR

Study Details

The goal of STAGE I of the CMV TransmIT Study is to determine the prevalence of CMV shedding in children up to and including 36 months of age in large group childcare centers and in staff who regularly work at the center. Participants will complete a health survey and provide one saliva sample for CMV PCR testing. In addition, infrastructure for the study will be developed (e.g. community engagement to build the network of centers, data pipelines, digital platform, sampling workflows) and participant sample collection at home will be piloted. These activities will inform the design of STAGE II.

Key Dates

Start date
Aug 10, 2023
Status verified
Jul 2024
Primary completion
Jan 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Children
    Children up to and including 36 months in large group childcare centers in the study network
  • Arm: Staff
    All staff members in large group childcare centers attended by children participants

Primary Outcome Measure

Prevalence of CMV shedding [ Time Frame: Stage I up to 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UMass Chan Medical SchoolWorcesterMassachusetts01655-

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By research site
UMass Chan Medical School· Worcester, MA

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