Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Part of paid clinical trials in Towson, Maryland.

Sponsor: University of Maryland St. Joseph Medical Center
Study ID: NCT06513208
Phase: PHASE4
Status: Recruiting

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Conditions

Lumbar Spinal Fusion

Eligibility Criteria

Sex: ALL
Age: 18 Years - 85 Years
Healthy Volunteers: Accepted

Interventions

Ketorolac Tromethamine — DRUG
IV Ketorolac 15mg every 6 hours, x 4 doses
Placebo — DRUG
IV saline as placebo

Study Details

A double blind prospective randomized trial of IV ketorolac vs. placebo in management of patients undergoing lumbar one or two level spinal fusions.

Key Dates

Start date: Jan 31, 2026
Status verified: Dec 2025
Primary completion: Jun 30, 2027
Completion: Jun 30, 2027

Study Design

Enrollment: 140 participants (estimated)
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Arms

Active Comparator: Ketorolac arm
Placebo Comparator: Placebo Arm

Primary Outcome Measure

Ketorolac results in decreased post-op opioid use when administered in the first 48 hours (measured by calculating the total amount of MME utilized during the patient's inpatient stay and comparing the control and experimental groups). [ Time Frame: 12 months ]

Central Contacts

Aja Janyavula
410-427-5459
[email protected]
Sam Rudow
410-427-5459
[email protected]

Locations (1)

Facility	City	State	ZIP	Site coordinators
University of Maryland St. Joseph Medical Center	Towson	Maryland	21204	Sam Rudow [email protected] 410-427-5459 Justin Tortolani, MD (PRINCIPAL_INVESTIGATOR)

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By research site

University of Maryland St. Joseph Medical Center· Towson, MD