Low-Dose Ketamine Infusion During Burn Wound Care

Part of paid clinical trials in Memphis, Tennessee.

Sponsor
University of Tennessee
Study ID
NCT06506565
Phase
PHASE4
Status
Recruiting
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Conditions

  • Burn
  • Dissociation
  • Opioid
  • Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Ketamine — DRUG
    Infusion during wound care
  • 0.9% NaCl — DRUG
    Infusion during wound care

Study Details

The current standard of care (SOC) (i.e. fentanyl and midazolam) offers limited efficacy for preventing or relieving pain. Ketamine infusions may provide the benefits of analgesia, minimize adverse events, and reduce opioid use. The purpose of this study is to determine if adding a low dose ketamine infusion during wound care will safely provide pain relief for patients with burn injury.

Key Dates

Start date
Jul 8, 2024
Status verified
Dec 2024
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
140 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Ketamine
    Ketamine infusion (0.3 mg/kg/hr) to begin 1 hour before wound care, continuing through and for 1 hour following wound care.
  • Placebo Comparator: Placebo
    0.9% saline to begin 1 hour before wound care, continuing through and for 1 hour following wound care.

Primary Outcome Measure

Analgesia [ Time Frame: up to 7 days from enrollment ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Regional One HealthMemphisTennessee38103
Yvonne Shaw, RN
[email protected]
901-448-2714

Find similar trials in Memphis, TN

By research site
Regional One Health· Memphis, TN

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