Understanding the Acute Pain Phenotype in Patients Undergoing Surgery

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Brigham and Women's Hospital
Study ID
NCT06466941
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • regional anesthesia — PROCEDURE
    Patients who underwent surgery and received an epidural or peripheral nerve block
  • no regional anesthesia — PROCEDURE
    Patients who underwent surgery and did not received an epidural or peripheral nerve block
  • acute pain consultation — OTHER
    Patients who underwent surgery and had a perioperative (preop, intraop, or postop) acute pain consultation
  • no acute pain consultation — OTHER
    Patients who underwent surgery and did not have a perioperative (preop, intraop, or postop) acute pain consultation

Study Details

The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and anxiety, who are having surgery. The main questions are: 1. Do psychosocial factors such as concerns about pain, sleep, anxiety affect the effectiveness of regional anesthesia? 2. Do psychosocial factors and regional anesthesia affect the amount of opioids used after surgery? 3. Do psychosocial factors and regional anesthesia affect development of chronic postsurgical pain?

Key Dates

Start date
Jul 3, 2024
Status verified
May 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2028

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: Thoracic surgery and open abdominal surgery
    Patients who underwent surgery thoracic surgery or open abdominal surgery
  • Arm: Orthopedic surgery
    Patients who underwent orthopedic surgery
  • Arm: Spine surgery
    Patients who underwent spine surgery

Primary Outcome Measure

Maximum pain score over the first 24 hours after surgery [ Time Frame: 0-24 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Brigham and Women's HospitalBostonMassachusetts02115
Yun-Yun Chen, MD
[email protected]
(617) 798-0290‬

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