Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

Part of paid clinical trials in Atlanta, Georgia.

Sponsor
Sohag University
Study ID
NCT06453252
Status
Not Yet Recruiting

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Conditions

  • Intracranial Atherosclerosis
  • Posterior Circulation Brain Infarction
  • Stroke, Ischemic

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • we are aiming to develop a Scoring system based on certain variables derived from both groups — OTHER
    We are aiming to develop a Scoring system based on certain variables derived from both group

Study Details

Early identification of intracranial atherosclerotic disease (ICAD) may impact the management of patients undergoing mechanical thrombectomy (MT). The aim of the study is to develop and validate a scoring system for pre-thrombectomy diagnosis of ICAD in posterior circulation large vessel/distal medium vessel occlusion strokes (LVOs/DMVOs).

Key Dates

Start date
Aug 1, 2024
Status verified
Jul 2024
Primary completion
Jun 1, 2025
Completion
Jun 30, 2026

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: ICAD group
    includes ICAD-related stroke made when a smooth-bordered lesions leading to delayed perfusion on conventional-angiography (without competing stroke etiology) or when irregular-surfaced lesions involving the target vessel during mechanical thrombectomy were unveiled (with or without competing stroke etiology).
  • Arm: Non-ICAD cases (controls)
    Non-ICAD cases (controls) includes patients with posterior circulation stroke attributed to stroke etiologies other than ICAD.

Primary Outcome Measure

Post-procedural outcomes included any intracranial hemorrhage, symptomatic ICH (sICH) [ Time Frame: June 1st, 2025 ]

Locations (1)

FacilityCityStateZIPSite coordinators
Marcus stroke and neuroscience center, Grady Memorial HospitalAtlantaGeorgia30303
Diogo C Haussen, MD
[email protected]
786-280-2098
Mohamed A Tarek, MD,MSc (SUB_INVESTIGATOR)

Find similar trials in Atlanta, GA

By research site
Marcus stroke and neuroscience center, Grady Memorial Hospital· Atlanta, GA

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