Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome

Part of paid clinical trials in Columbia, Missouri.

Sponsor
University of Missouri-Columbia
Study ID
NCT06433115
Status
Recruiting

Conditions

  • Diet Intervention

Eligibility Criteria

Sex
ALL
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Lean (≥90%) Grass-Fed Beef — OTHER
    The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal.
  • Lean (≥90%) Grain-Fed Beef — OTHER
    The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal.
  • Plant-Based Meat — OTHER
    Plant-based meat would be macronutrient matched to the same quantities of meat prescribed for a given energy level.

Study Details

This study is investigating the benefits of lean beef consumption on cardiometabolic health and gut microbiome.

Key Dates

Start date
Jun 11, 2024
Status verified
Jul 2025
Primary completion
Dec 1, 2027
Completion
Dec 1, 2027

Study Design

Enrollment
90 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Lean (≥90%) Grass-Fed Beef
    The quantity of beef will be adjusted or normalized based on their individual energy requirements. The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal. Participants will consume meals for six weeks.
  • Experimental: Lean (≥90%) Grain-Fed Beef
    The quantity of beef will be adjusted or normalized based on their individual energy requirements. The specified amount will be 4 oz. per day or 28 ounces per week for participants with an energy requirement of 2000 kcal. Participants will consume meals for six weeks.
  • Active Comparator: Plant-Based Meat
    Plant-based meat (beyond meat product) would be macronutrient matched to the same quantities of meat prescribed for a given energy level. Participants will consume meals for six weeks.

Primary Outcome Measure

LDL-C concentrations [ Time Frame: Baseline, week 6 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Missouri-ColumbiaColumbiaMissouri65211
Jaapna Dhillon
573-884-2103
Jaapna Dhillon, PhD (PRINCIPAL_INVESTIGATOR)

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